diff --git a/frontend/src/hooks/useSettingsData.ts b/frontend/src/hooks/useSettingsData.ts
index 270e9ff..a376244 100644
--- a/frontend/src/hooks/useSettingsData.ts
+++ b/frontend/src/hooks/useSettingsData.ts
@@ -11,6 +11,7 @@ interface RoutingConfig {
 
 interface InstallConfig {
   pythonIndexUrl: string;
+  npmRegistry: string;
 }
 
 interface SystemSettings {
@@ -28,9 +29,9 @@ export const useSettingsData = () => {
     enableGlobalRoute: true,
     enableGroupNameRoute: true,
   });
-
   const [installConfig, setInstallConfig] = useState<InstallConfig>({
     pythonIndexUrl: '',
+    npmRegistry: '',
   });
 
   const [loading, setLoading] = useState(false);
@@ -67,10 +68,10 @@ export const useSettingsData = () => {
           enableGroupNameRoute: data.data.systemConfig.routing.enableGroupNameRoute ?? true,
         });
       }
-
       if (data.success && data.data?.systemConfig?.install) {
         setInstallConfig({
           pythonIndexUrl: data.data.systemConfig.install.pythonIndexUrl || '',
+          npmRegistry: data.data.systemConfig.install.npmRegistry || '',
         });
       }
     } catch (error) {
diff --git a/frontend/src/locales/en.json b/frontend/src/locales/en.json
index 1ba17e2..b4cb2ec 100644
--- a/frontend/src/locales/en.json
+++ b/frontend/src/locales/en.json
@@ -247,6 +247,9 @@
     "pythonIndexUrl": "Python Package Repository URL",
     "pythonIndexUrlDescription": "Set UV_DEFAULT_INDEX environment variable for Python package installation",
     "pythonIndexUrlPlaceholder": "e.g. https://pypi.org/simple",
+    "npmRegistry": "NPM Registry URL",
+    "npmRegistryDescription": "Set npm_config_registry environment variable for NPM package installation",
+    "npmRegistryPlaceholder": "e.g. https://registry.npmjs.org/",
     "installConfig": "Installation Configuration",
     "systemConfigUpdated": "System configuration updated successfully"
   }
diff --git a/frontend/src/locales/zh.json b/frontend/src/locales/zh.json
index 37a7d50..98a8bc8 100644
--- a/frontend/src/locales/zh.json
+++ b/frontend/src/locales/zh.json
@@ -248,6 +248,9 @@
     "pythonIndexUrl": "Python 包仓库地址",
     "pythonIndexUrlDescription": "设置 UV_DEFAULT_INDEX 环境变量，用于 Python 包安装",
     "pythonIndexUrlPlaceholder": "例如: https://mirrors.aliyun.com/pypi/simple",
+    "npmRegistry": "NPM 仓库地址",
+    "npmRegistryDescription": "设置 npm_config_registry 环境变量，用于 NPM 包安装",
+    "npmRegistryPlaceholder": "例如: https://registry.npmmirror.com/",
     "installConfig": "安装配置",
     "systemConfigUpdated": "系统配置更新成功"
   }
diff --git a/frontend/src/pages/SettingsPage.tsx b/frontend/src/pages/SettingsPage.tsx
index cf16c2c..d4df296 100644
--- a/frontend/src/pages/SettingsPage.tsx
+++ b/frontend/src/pages/SettingsPage.tsx
@@ -16,11 +16,12 @@ const SettingsPage: React.FC = () => {
   useEffect(() => {
     setCurrentLanguage(i18n.language);
   }, [i18n.language]);
-
   const [installConfig, setInstallConfig] = useState<{
     pythonIndexUrl: string;
+    npmRegistry: string;
   }>({
     pythonIndexUrl: '',
+    npmRegistry: '',
   });
 
   const {
@@ -54,16 +55,15 @@ const SettingsPage: React.FC = () => {
   const handleRoutingConfigChange = async (key: 'enableGlobalRoute' | 'enableGroupNameRoute', value: boolean) => {
     await updateRoutingConfig(key, value);
   };
-
-  const handleInstallConfigChange = (value: string) => {
+  const handleInstallConfigChange = (key: 'pythonIndexUrl' | 'npmRegistry', value: string) => {
     setInstallConfig({
       ...installConfig,
-      pythonIndexUrl: value
+      [key]: value
     });
   };
 
-  const saveInstallConfig = async () => {
-    await updateInstallConfig('pythonIndexUrl', installConfig.pythonIndexUrl);
+  const saveInstallConfig = async (key: 'pythonIndexUrl' | 'npmRegistry') => {
+    await updateInstallConfig(key, installConfig[key]);
   };
 
   const handlePasswordChangeSuccess = () => {
@@ -87,21 +87,19 @@ const SettingsPage: React.FC = () => {
           <h2 className="font-semibold text-gray-800">{t('pages.settings.language')}</h2>
           <div className="flex space-x-3">
             <button
-              className={`px-3 py-1.5 rounded-md transition-colors text-sm ${
-                currentLanguage.startsWith('en') 
-                  ? 'bg-blue-500 text-white' 
-                  : 'bg-blue-100 text-blue-800 hover:bg-blue-200'
-              }`}
+              className={`px-3 py-1.5 rounded-md transition-colors text-sm ${currentLanguage.startsWith('en')
+                ? 'bg-blue-500 text-white'
+                : 'bg-blue-100 text-blue-800 hover:bg-blue-200'
+                }`}
               onClick={() => handleLanguageChange('en')}
             >
               English
             </button>
             <button
-              className={`px-3 py-1.5 rounded-md transition-colors text-sm ${
-                currentLanguage.startsWith('zh') 
-                  ? 'bg-blue-500 text-white' 
-                  : 'bg-blue-100 text-blue-800 hover:bg-blue-200'
-              }`}
+              className={`px-3 py-1.5 rounded-md transition-colors text-sm ${currentLanguage.startsWith('zh')
+                ? 'bg-blue-500 text-white'
+                : 'bg-blue-100 text-blue-800 hover:bg-blue-200'
+                }`}
               onClick={() => handleLanguageChange('zh')}
             >
               中文
@@ -174,13 +172,37 @@ const SettingsPage: React.FC = () => {
                 <input
                   type="text"
                   value={installConfig.pythonIndexUrl}
-                  onChange={(e) => handleInstallConfigChange(e.target.value)}
+                  onChange={(e) => handleInstallConfigChange('pythonIndexUrl', e.target.value)}
                   placeholder={t('settings.pythonIndexUrlPlaceholder')}
                   className="flex-1 mt-1 block w-full py-2 px-3 border border-gray-300 rounded-md shadow-sm focus:outline-none focus:ring-blue-500 focus:border-blue-500 sm:text-sm"
                   disabled={loading}
                 />
                 <button
-                  onClick={saveInstallConfig}
+                  onClick={() => saveInstallConfig('pythonIndexUrl')}
+                  disabled={loading}
+                  className="mt-1 px-4 py-2 bg-blue-600 hover:bg-blue-700 text-white rounded-md text-sm font-medium disabled:opacity-50"
+                >
+                  {t('common.save')}
+                </button>
+              </div>
+            </div>
+
+            <div className="p-3 bg-gray-50 rounded-md">
+              <div className="mb-2">
+                <h3 className="font-medium text-gray-700">{t('settings.npmRegistry')}</h3>
+                <p className="text-sm text-gray-500">{t('settings.npmRegistryDescription')}</p>
+              </div>
+              <div className="flex items-center gap-3">
+                <input
+                  type="text"
+                  value={installConfig.npmRegistry}
+                  onChange={(e) => handleInstallConfigChange('npmRegistry', e.target.value)}
+                  placeholder={t('settings.npmRegistryPlaceholder')}
+                  className="flex-1 mt-1 block w-full py-2 px-3 border border-gray-300 rounded-md shadow-sm focus:outline-none focus:ring-blue-500 focus:border-blue-500 sm:text-sm"
+                  disabled={loading}
+                />
+                <button
+                  onClick={() => saveInstallConfig('npmRegistry')}
                   disabled={loading}
                   className="mt-1 px-4 py-2 bg-blue-600 hover:bg-blue-700 text-white rounded-md text-sm font-medium disabled:opacity-50"
                 >
diff --git a/src/controllers/serverController.ts b/src/controllers/serverController.ts
index 22b798c..6eea77a 100644
--- a/src/controllers/serverController.ts
+++ b/src/controllers/serverController.ts
@@ -289,7 +289,8 @@ export const updateSystemConfig = (req: Request, res: Response): void => {
       (!routing ||
         (typeof routing.enableGlobalRoute !== 'boolean' &&
           typeof routing.enableGroupNameRoute !== 'boolean')) &&
-      (!install || typeof install.pythonIndexUrl !== 'string')
+      (!install ||
+        (typeof install.pythonIndexUrl !== 'string' && typeof install.npmRegistry !== 'string'))
     ) {
       res.status(400).json({
         success: false,
@@ -321,6 +322,7 @@ export const updateSystemConfig = (req: Request, res: Response): void => {
     if (!settings.systemConfig.install) {
       settings.systemConfig.install = {
         pythonIndexUrl: '',
+        npmRegistry: '',
       };
     }
 
@@ -333,11 +335,13 @@ export const updateSystemConfig = (req: Request, res: Response): void => {
         settings.systemConfig.routing.enableGroupNameRoute = routing.enableGroupNameRoute;
       }
     }
-
     if (install) {
       if (typeof install.pythonIndexUrl === 'string') {
         settings.systemConfig.install.pythonIndexUrl = install.pythonIndexUrl;
       }
+      if (typeof install.npmRegistry === 'string') {
+        settings.systemConfig.install.npmRegistry = install.npmRegistry;
+      }
     }
 
     if (saveSettings(settings)) {
diff --git a/src/services/mcpService.ts b/src/services/mcpService.ts
index c0056f9..5e85744 100644
--- a/src/services/mcpService.ts
+++ b/src/services/mcpService.ts
@@ -91,11 +91,19 @@ export const initializeClientsFromSettings = (isInit: boolean): ServerInfo[] =>
       env['PATH'] = expandEnvVars(process.env.PATH as string) || '';
 
       // Add UV_DEFAULT_INDEX from settings if available (for Python packages)
-      const settings = loadSettings();
+      const settings = loadSettings(); // Add UV_DEFAULT_INDEX from settings if available (for Python packages)
       if (settings.systemConfig?.install?.pythonIndexUrl && conf.command === 'uvx') {
         env['UV_DEFAULT_INDEX'] = settings.systemConfig.install.pythonIndexUrl;
       }
 
+      // Add npm_config_registry from settings if available (for NPM packages)
+      if (
+        settings.systemConfig?.install?.npmRegistry &&
+        (conf.command === 'npm' || conf.command === 'npx')
+      ) {
+        env['npm_config_registry'] = settings.systemConfig.install.npmRegistry;
+      }
+
       transport = new StdioClientTransport({
         command: conf.command,
         args: conf.args,
diff --git a/src/types/index.ts b/src/types/index.ts
index 7e8038f..2aa2761 100644
--- a/src/types/index.ts
+++ b/src/types/index.ts
@@ -86,6 +86,7 @@ export interface McpSettings {
     };
     install?: {
       pythonIndexUrl?: string; // Python package repository URL (UV_DEFAULT_INDEX)
+      npmRegistry?: string; // NPM registry URL (npm_config_registry)
     };
     // Add other system configuration sections here in the future
   };